Typhidot

440.00

Typhidot is a medical test consisting of a dot ELISA kit[1] that detects IgM and IgG antibodies against the outer membrane protein (OMP) of the Salmonella typhi. The typhidot test becomes positive within 2–3 days of infection and separately identifies IgM and IgG antibodies. The test is based on the presence of specific IgM and IgG antibodies to a specific 50Kd OMP antigen, which is impregnated on nitrocellulose strips.

 

SPECIMEN: 2 mL (1 mL min.) serum from 1 SST. Ship refrigerated or frozen.

 

STABILITY: Room: 8 hrs; Refrigerated: 5 days Frozen: 2 weeks

 

REPORT: Daily

 

PRE-TEST INFORMATION: No special preparation required.

 

USAGE: Scrub Typhus is an infectious disease that is caused by Orientia tsutsugamushi a bacteria that belongs to family of Rickettsiaceae. A bite from a trombiculid larval mite, followed by symptoms including fever, a spotted rash on torso, black eschar at the site of mite bite, body & muscle pain and swelling of lymph glands. After the onset of symptoms, the IgM antibody titers increase gradually over 2-3 weeks and peak at about 4 weeks. Common complications associated with Scrub typhus are acute kidney injury, hepatitis, acute respiratory distress syndrome (ARDS), meningoencephalitis, myocarditis and septic shock.
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