CD5 is expressed normally on all T cells (one of the pan T-cell antigens). It can be aberrantly expressed by B-cell lymphomas, most commonly Mantle cell lymphoma & B-cell Small lymphocytic lymphoma. Expression of CD5 is useful to support T-cell lineage in T-cell lymphomas or to help subclassify B-cell lymphomas.

SPECIMEN: Submit Tissue in 10% formal-saline OR formalin fixed paraffin embedded Tissue Block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
STABILITY: Room: NA; Refrigerated: NA; Frozen: NA
REPORT: After 2 days
INSTRUCTIONS: Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
USAGE: CD5 is expressed normally on all T cells (one of the pan T-cell antigens). It can be aberrantly expressed by B-cell lymphomas, most commonly Mantle cell lymphoma & B-cell Small lymphocytic lymphoma. Expression of CD5 is useful to support T-cell lineage in T-cell lymphomas or to help subclassify B-cell lymphomas.